Apoptosis in Toxicology is the primary e book to concentrate on the molecular regulation of apoptosis with specific emphasis on toxicant action. Cell survival signalling and its perturbation is addressed on the genetic and biochemical stage, including key survival and demise genes, survival signalling, dedication to apoptosis and recruitment of the initiator and executioner caspases.
Emphasis is given to the position apoptosis performs within the action of toxicants within the brain, the immune system, the reproductive organs, the kidney and the liver. The ability of medication to regulate apoptosis either as a goal or as an antagonistic effect is discussed with particular reference to cancer chemotherapy. The various methods that may be employed to quantify apoptosis are in contrast and their software to completely different tissues is discussed.
This well timed and comprehensive quantity has been written by leading authorities and active researchers of their respective fields. It can have broad enchantment to toxicologists, physicians and biologists across many disciplines.
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